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Risk Assessment, within the field of Toxicology and Environmental Health, is a systematic process used to evaluate and estimate the potential harm or adverse health effects that may result from exposure to a hazardous substance or situation. It involves identifying and characterizing the hazard, evaluating the exposure levels, estimating the likelihood and severity of potential health impacts, and determining the overall level of risk associated with the exposure. Risk assessment plays a crucial role in protecting both human health and the environment by providing decision-makers with the necessary information to take appropriate actions to reduce or eliminate risks. It is an essential tool for informing policy and regulatory decisions related to chemical management, occupational health and safety, environmental protection, and public health. Within the hierarchy of Health, Environmental Health, Toxicology, Risk Assessment, risk assessment represents the application of toxicological principles and methods to evaluate and manage potential health risks associated with exposure to hazardous substances or situations. It builds upon the foundational knowledge and expertise in environmental health and toxicology to provide a more comprehensive understanding of the potential impacts of chemical exposures on human health and the environment.